Spatial data science

The field of data science has had a significant impact in both academia and industry, and with good reason [...]This research was partially funded by the Portuguese Foundation for Science and Technology (FCT),under projects IPSTERS (DSAIPA/AI/0100/2018), and foRESTER (PCIF/SSI/0102/2017)

Experiencias vividas en una prolongada relación entrenador-atleta. El caso de un atleta paralímpico

The purpose of the present study was to explore the lived experiences of one male Paralympic athlete who maintained a longstanding relationship with his coach. This case provides insight into how a coach can serve as a key supportive agent in enabling an athlete to thrive both in sport and in life. The athlete was interviewed on two separate occasions and an interpretative phenomenological analysis was conducted. The athlete discussed the consequences of an acute bout of meningitis experienced at four years of age that left him impaired. During adolescence and adulthood, the athlete experienced the death of his mother and sister as well as the challenges associated with him assuming his homosexuality. Throughout these ordeals, his coach acted as a constant support figure. The athlete attributed much weight to his coach’s trust, respect, and empathy in explaining the significant success he attained on the international stage. The recommendations offered focus on how coaches can support athletes when athletes are navigating tough challenges

Integrating Positive Youth Development within Coach Education for Youth Sport Coaches

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Youth sport coaches’ role in facilitating positive youth development in Portuguese field hockey

Researchers have examined youth sport coaches’ role in facilitating positive youth development (PYD). This past research demonstrates that when coaches use an intentional approach to development, they can play an important part in helping young people to reach adulthood with the necessary competencies to face the social challenges ahead. However, studies within the area of PYD through sport have predominantly emanated from Englishspeaking countries and there remains a need to better understand coaches’ views on PYD within different countries’ sport systems. The purpose of this study was to examine Portuguese coaches’ perspectives on their role in facilitating PYD in youth field hockey. The participants were 11 youth field hockey coaches (2 females and 9 males) who coached athletes between 6 and 18 years of age. Findings showed how the coaches believed PYD could be fostered as they discussed several PYD-related concepts (e.g. life skills) they deemed were being developed in field hockey. However, creating enjoyable environments and talking about life skills with players were the only explicit initiatives discussed by the coaches with the intent of fostering PYD. Coach education was perceived by half the sample as an important learning situation to gain competencies to facilitate PYD, while the other half emphasised that coach education courses were lacking in material associated with this topic. Those who saw value in coach education presented a narrow view of PYD as being solely associated with the psychological aspects of coaching. Moving forward, coach education courses should first be designed to have coaches understand the full spectrum of the concept of PYD and be framed as suitable learning environments where coaches can learn how to foster PYD.info:eu-repo/semantics/publishedVersio

Analyzing continuous coach education courses in Portugal: Implications for youth development

Continuous coach education courses (CCEC) are considered a crucial vehicle for exposing coaches to topics (e.g., nutrition, mental health, positive youth development) not addressed in their initial coach training. CCEC can help coaches develop well-rounded coaching practices based on youth's physical, social, emotional, and psychological needs. The purpose of the study was to analyze the distribution of CCEC offered in Portugal between 2014 and 2020. Descriptive and inferential statistics were used to analyze (a) the number of CCEC offered; (b) hours devoted to each topic; (c) the types of organizations who delivered CCEC; (e) the format of CCEC (i.e., online or in-person); (f) the geographical distribution of CCEC throughout Portugal; (g) the number of coach participants per topic. The results indicate that courses addressing mental health, social justice, positive youth development, and sleep hygiene are seldomly delivered in Portugal, meaning that coaches have few opportunities to be exposed to and learn about these important topics. Thus, our results suggest CCEC in Portugal may not be extending coaches’ knowledge much beyond topics covered in their initial coach training. The lack of breadth in training may help perpetuate the emphasis on the technical, tactical, and physical development of youth with the Portuguese youth sport system. Based on the results, implications for youth development are offered

An operational framework for integrated Mapping and Assessment of Ecosystems and their Services (MAES)

Mapping and Assessment of Ecosystems and their Services (MAES) are central to the EU Biodiversity Strategy to 2020. Action 5 of the Strategy’s second target asks all EU member states to map and assess the state of ecosystems and their services in their national territories. Such comprehensive mapping and assessment builds on several individual tasks and their systematic integration. Therefore, an integrated and operational framework is needed, supporting and coordinating these activities. The presented framework builds on existing work done by the European Commission’s MAES Working Group and provides a clear nine-step approach including the identification of relevant questions or themes to be addressed, identification and mapping of ecosystem types, ecosystem condition and ecosystem services, their integration and dissemination of results. This framework can be used to set-up related research and development initiatives and to guide involved scientists, decision-makers and practitioners through the different steps and related tasks of the process

The Intestinal Gas Questionnaire (IGQ): Psychometric validation of a new instrument for measuring gas-related symptoms and their impact on daily life among general population and irritable bowel syndrome

Gas-related symptoms; Patient-reported outcomes; Quality of lifeSíntomas relacionados con los gases; Resultados informados por el paciente; Calidad de vidaSímptomes relacionats amb els gasos; Resultats informats pel pacient; Qualitat de vidaBackground Gas-related symptoms (GRS) are common in the general population (GPop) and among patients with disorders of gut-brain interactions but there is no patient-reported outcome evaluating these symptoms and their impact on daily life. We have previously developed a 43-item intestinal gas questionnaire (IGQ). The aim of the present study is to perform a psychometric validation of this instrument. Methods Participants (119 from the GPop and 186 irritable bowel syndrome (IBS) patients) were recruited from 3 countries (UK, Spain, France). IBS patients fulfilled ROME IV criteria with an IBS severity score between 150 and 300. Participants completed the IGQ, the functional Digestive Disorders Quality of Life (FDDQL), and the EQ-5D. A subgroup (n = 90) repeated the IGQ completion after 7 days on paper or electronically. Results From the original IGQ questionnaire, 26 items were deleted because of poor performance. Confirmatory factorial analysis on the remaining 17 items (7 symptom and 10 impact items) yielded a 6-factor structure accounting for 67% of the variance for bloating (6 items), flatulence (3), belching (2), bad breath (2), stomach rumbling (2), and difficult gas evacuation (2). Global score (0-100) was worse among IBS vs GPop (40 ± 15 vs 33 ± 17; p = 0.0016). At the second visit, the intraclass correlation coefficient of IGQ scores was between 0.71 and 0.86 (n = 67) for test-retest reliability and 0.61-0.87 (n = 64) for equivalence between electronic and paper versions of IGQ. Conclusion The IGQ available in paper and electronic versions in 3 languages is a robust instrument for capturing and measuring GRS and their impact on daily life.This Investigator Sponsored Study has been funded by Danone Research. Danone did not interfere with the analysis and interpretation of data. The work was supported in part by the Spanish Ministry of Economy and Competitiveness (Dirección General de Investigación Científica y Técnica, SAF 2016-76648-R). Ciberehd is funded by the Instituto de Salud Carlos II

Reconstructing Viral Genomes from the Environment Using Fosmid Clones: The Case of Haloviruses

Background: Metaviriomes, the viral genomes present in an environment, have been studied by direct sequencing of the viral DNA or by cloning in small insert libraries. The short reads generated by both approaches make it very difficult to assemble and annotate such flexible genomic entities. Many environmental viruses belong to unknown groups or prey on uncultured and little known cellular lineages, and hence might not be present in databases. Methodology and Principal Findings: Here we have used a different approach, the cloning of viral DNA into fosmids before sequencing, to obtain natural contigs that are close to the size of a viral genome. We have studied a relatively low diversity extreme environment: saturated NaCl brines, which simplifies the analysis and interpretation of the data. Forty-two different viral genomes were retrieved, and some of these were almost complete, and could be tentatively identified as head-tail phages (Caudovirales). Conclusions and Significance: We found a cluster of phage genomes that most likely infect Haloquadratum walsbyi, the square archaeon and major component of the community in these hypersaline habitats. The identity of the prey could be confirmed by the presence of CRISPR spacer sequences shared by the virus and one of the available strain genomes. Other viral clusters detected appeared to prey on the Nanohaloarchaea and on the bacterium Salinibacter ruber, covering most of the diversity of microbes found in this type of environment. This approach appears then as a viable alternative to describe metaviriomes in a much more detailed and reliable way than by the more common approaches based on direct sequencing. An example of transfer of a CRISPR cluster including repeats and spacers was accidentally found supporting the dynamic nature and frequent transfer of this peculiar prokaryotic mechanism of cell protection.This work was supported by projects MAGYK (BIO2008-02444), MICROGEN (Programa CONSOLIDERINGENIO 2010 CDS2009-00006), CGL2'09-12651-C02-01 from the Spanish Ministerio de Ciencia e Innovación, DIMEGEN (PROMETEO/2010/089) and ACOMP/2009/155 from the Generalitat Valenciana. FEDER funds supported this project. IG-H was supported by MAGYK from Ministerio de Ciencia e Innovación. A-BM-C was supported by CONSOLIDER-INGENIO 2010

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival

et al.Sos1 and Sos2 are ubiquitously expressed, universal Ras guanine nucleotide exchange factors (Ras-GEFs) acting in multiple signal transduction pathways activated by upstream cellular kinases. The embryonic lethality of Sos1 null mutants has hampered ascertaining the specific in vivo contributions of Sos1 and Sos2 to processes controlling adult organism survival or development of hematopoietic and nonhematopoietic organs, tissues, and cell lineages. Here, we generated a tamoxifen-inducible Sos1-null mouse strain allowing analysis of the combined disruption of Sos1 and Sos2 (Sos1/2) during adulthood. Sos1/2 double-knockout (DKO) animals died precipitously, whereas individual Sos1 and Sos2 knockout (KO) mice were perfectly viable. A reduced percentage of total bone marrow precursors occurred in single-KO animals, but a dramatic depletion of B-cell progenitors was specifically detected in Sos1/2 DKO mice. We also confirmed a dominant role of Sos1 over Sos2 in early thymocyte maturation, with almost complete thymus disappearance and dramatically higher reduction of absolute thymocyte counts in Sos1/2 DKO animals. Absolute counts of mature B and T cells in spleen and peripheral blood were unchanged in single-KO mutants, while significantly reduced in Sos1/2 DKO mice. Our data demonstrate functional redundancy between Sos1 and Sos2 for homeostasis and survival of the full organism and for development and maturation of T and B lymphocytes.Work was supported by grants FIS-PS09/01979, RTICC-RD12/0036/0001, and RD12/0036/0048 from Instituto de Salud Carlos III (Madrid, Spain) and Fundación Samuel Solórzano (Salamanca, Spain). This research was also supported by the Intramural Research Program of the CCR, NCI, NIH.Peer Reviewe

Proyecto centro de turismo rural, en Cuellar (Segovia)

Se redacta el presente Proyecto Básico y de Ejecución de un Centro de turismo rural. El edificio se ubica en la parte noreste de la población y está delimitado por una edificación medianera, Av. Camilo José Cela, Av. de la Concepción y la C/ del Rosario. En Cuellar (Segovia) Está conformado por tres viviendas y dos locales, comunicadas en altura por el núcleo de escaleras (sin ascensor) que se ubica en el centro del edificio y dos locales en planta baja, uno con entrada independiente desde la C/ del Rosario. realizádos en el año 1910, según datos catastrales. Tiene forma geométrica en planta de polígono irregular con unas dimensiones de los lados de 12,62 m, 8,24 m, 11,68 m y 15,21 m de longitud, una superficie construida total de 410,75 m2 y, una superficie ocupada en planta baja de 136,21 m²